ABSTRACT
OBJECTIVE: To determine the prevalence of hypomagnesemia in diabetic children during diabetic ketoacidosis and following restitution of acid-base balance. METHODS: Eight consecutive diabetic children, ranging in age from 8 to 16 years, hospitalized in the pediatric intensive care unit with diabetic ketoacidosis from October 1st. through December 31st, 1995. A control group of 33 metabolically stable diabetic children, and a control group of 30 healthy children. Both control groups were similar in composition regarding age and sex to the study group. None of the patients in the study group and none of the controls had Magnesium supplementation given to them during the study period. MEASUREMENTS: Total serum Magnesium concentrations were measured from peripheral venous blood in all 71 patients. For the study group serum Magnesium was determined in a serial fashion: 1. upon admission in diabetic ketoacidosis 2. 24 hours after admission 3. 72 hours after admission RESULTS: The prevalence of hypomagnesemia was 62.4 in patients with diabetic ketoacidosis, (Group 1), 25 in patients after partial correction of ketoacidosis, (Group 2), and none in patients after resolution of ketoacidosis, (Group 3). The prevalence of hypomagnesemia was 6 for the chronic, metabolically stable diabetic control group, (Group 4), but 0 for the non-diabetic control group, (Group 5). Average serum Magnesium levels were significantly lower (p less than 0.05), in patients admitted in diabetic ketoacidosis compared to those of both the diabetic and the non-diabetic control groups. Also average serum Magnesium levels were significantly lower (p less than 0.05), in patients with corrected diabetic ketoacidosis than those of the healthy control group. But there were no significant differences (p = 0.59263) in average serum Magnesium levels between the diabetic control group and the diabetic patients after resolution of ketoacidosis. CONCLUSIONS: In this study the prevalence of hypomagnesemia was documented to be higher than the average described elsewhere for pediatric, adult, and coronary intensive care units. As hypomagnesemia is an indication of Magnesium depletion, we speculate that the transient hypomagnesemia detected in our study group is an expression of a state of Magnesium depletion that is masked by correction of acidosis and the Magnesium shifts associated with it. Consequently serum Magnesium values ought to be considered most reliable during and not after correction of
Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Diabetic Ketoacidosis/blood , Magnesium/blood , Age Factors , Analysis of Variance , Bicarbonates/blood , Cross-Sectional Studies , Carbon Dioxide/blood , Blood Glucose/analysis , Hydrogen-Ion Concentration , Glycated Hemoglobin/analysis , Intensive Care Units, Pediatric , Time FactorsSubject(s)
Child, Preschool , Child , Adolescent , Adult , Middle Aged , Humans , Male , Female , Glucosephosphate Dehydrogenase Deficiency/complications , Hemoglobin C/genetics , Hemoglobin, Sickle/genetics , Black People , Costa RicaABSTRACT
Se informa el primer caso confirmado de radiculomielitis post-conjuntivitis hemorrágica aguda (CHA) ocurrido en Panamá y probablemente en el continente americano. Se describen sus características epidemiológicas, las manifestaciones clínicas y su diagnóstico virológico
Subject(s)
Adult , Humans , Female , Radiculopathy/microbiology , Conjunctivitis/microbiology , Enterovirus Infections/complicationsABSTRACT
Se informa la epidemia de meningitis viral por ECHO 4 ocurrida en la ciudad capital durante 1981, la cual resultó la más grande ocurrida en la historia de Panamá y una de las más grandes epidemias comprobadas en la literatura. Se describen sus características clínicas y epidemiológicas, y se analizan las interrogantes que surgieron en la comunidad durante el desarrollo de las mismas
Subject(s)
Child, Preschool , Child , Adolescent , Humans , Male , Female , Cricetinae , Enterovirus B, Human , Meningitis, Viral/epidemiology , Disease Outbreaks/epidemiology , PanamaSubject(s)
Pregnancy , Adolescent , Adult , Humans , Female , Toxoplasmosis , Pregnancy Complications, Infectious , Pregnancy Trimester, First , Serologic TestsABSTRACT
Se estudiaron los expedientes clinicos de todos los pacientes adultos que habian sido admitidos en el Hospital Santo Tomas (HST) con el diagnostico de fiebre reumatica, en el periodo comprendido entre 1973 y 1979, y se seleccionaron los de trece pacientes adultos que fueron atendidos en su primer episodio y que se ajustaban estrictamente a los criterios revisados de Jones. La mayoria (85%) de los pacientes seleccionados eran adultos jovenes, entre los 8 y los 28 anos de edad; siete (54%) eran del sexo femenino y seis (46%) eran del sexo masculino. Nueve pacientes (69%) procedian del area metropolitana y cuatro (31%) procedian del interior de la Republica. La artritis fue la manifestacion clinica mas frecuente y se presento en el 100% de los casos. Se caracterizo por afectar las grandes articulaciones, principalmente de las extremidades inferiores, y por se poliarticular, simetrica y aditiva, en el 85% de los casos. La clasica migratoriedad solo se presento en el 15% de los pacientes. La carditis fue leve y se observo en el 38% de los casos. En ninguno de los pacientes se presento eritema marginado, nodulos subcutaneos o corea